Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 6/20 | 0.36 |
| ▸ | ATM | Q13315 | 6/20 | 0.36 |
| ▸ | GCK | P35557 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14113578 | 0.85 | ESR1 (0.37) | MAPK14ATMAURKAKDRAURKB | |
| SCHEMBL13638583 | 0.81 | MAPK14 (0.35) | MAPK14ATMMAPTLMNAKMT2A | |
| SCHEMBL9922686 | 0.80 | P2RY12 (0.51) | MAPK14ATMTP53MAPTAURKA | |
| SCHEMBL12177317 | 0.79 | POLB (0.35) | IDO1TP53MAPTTDO2KMT2A | |
| SCHEMBL13182890 | 0.77 | POLB (0.34) | IDO1TDO2 | |
| SCHEMBL14113598 | 0.75 | MAPK14 (0.31) | MAPK14 | |
| SCHEMBL14113600 | 0.74 | P2RY12 (0.33) | — | |
| SCHEMBL9920095 | 0.74 | P2RY12 (0.51) | ATMTP53MAPTKMT2AAURKA | |
| SCHEMBL13638646 | 0.73 | ATM (0.42) | ATM | |
| SCHEMBL9922502 | 0.72 | MAPT (0.35) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622474-B2 | Asulfonyl(urea, thiourea, guanidine, cyanoguanidine) compounds; cardiovascular disorders; thrombosis | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-11-24 | — | — | US | disclosed |