Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.41 |
| ▸ | TERT | O14746 | 7/20 | 0.38 |
| ▸ | POT1 | Q9NUX5 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 3/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177370 | 0.99 | HRH3 (0.41) | HRH3KCNH2TERTPOT1MET | |
| SCHEMBL13638561 | 0.95 | KCNH2 (0.41) | HRH3KCNH2TERTPOT1P2RY12 | |
| SCHEMBL9922735 | 0.94 | P2RY12 (0.44) | HRH3KCNH2TERTPOT1MET | |
| SCHEMBL9922737 | 0.93 | P2RY12 (0.44) | HRH3KCNH2TERTPOT1MET | |
| SCHEMBL12177323 | 0.93 | TSHR (0.40) | METMEN1KMT2A | |
| SCHEMBL9923201 | 0.90 | P2RY12 (0.46) | HRH3KCNH2TERTPOT1P2RY12 | |
| SCHEMBL9923208 | 0.89 | P2RY12 (0.47) | HRH3KCNH2TERTPOT1P2RY12 | |
| SCHEMBL13638586 | 0.88 | P2RY12 (0.40) | P2RY12MEN1KMT2A | |
| SCHEMBL14113603 | 0.88 | MET (0.39) | HRH3KCNH2TERTPOT1MET | |
| SCHEMBL14113594 | 0.88 | HRH3 (0.42) | HRH3KCNH2TERTPOT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622474-B2 | Asulfonyl(urea, thiourea, guanidine, cyanoguanidine) compounds; cardiovascular disorders; thrombosis | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-11-24 | — | — | US | disclosed |