Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CXCR3 | P49682 | 10/20 | 0.45 |
| ▸ | VDAC2 | P45880 | 1/20 | 0.45 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13633593 | 0.91 | VDAC2 (0.49) | ALDH1A1CXCR3VDAC2SLC7A11KMT2A | |
| SCHEMBL13633693 | 0.91 | VDAC2 (0.49) | ALDH1A1CXCR3VDAC2SLC7A11KMT2A | |
| SCHEMBL13633586 | 0.91 | VDAC2 (0.49) | ALDH1A1CXCR3VDAC2SLC7A11KMT2A | |
| SCHEMBL13633710 | 0.91 | VDAC2 (0.49) | ALDH1A1CXCR3VDAC2SLC7A11KMT2A | |
| SCHEMBL13633694 | 0.91 | VDAC2 (0.49) | ALDH1A1CXCR3VDAC2SLC7A11KMT2A | |
| SCHEMBL13633701 | 0.90 | VDAC2 (0.58) | CXCR3VDAC2SLC7A11 | |
| SCHEMBL13633734 | 0.90 | VDAC2 (0.50) | ALDH1A1CXCR3VDAC2SLC7A11KMT2A | |
| SCHEMBL13633679 | 0.87 | VDAC2 (0.51) | ALDH1A1VDAC2SLC7A11KMT2ATP53 | |
| SCHEMBL14468481 | 0.87 | VDAC2 (0.56) | ALDH1A1CXCR3VDAC2SLC7A11CHEK1 | |
| SCHEMBL13633683 | 0.80 | VDAC2 (0.53) | ALDH1A1VDAC2SLC7A11KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7615554-B2 | Erastin and erastin binding proteins, and uses thereof | PROLEXYS PHARMACEUTICALS, INC. (US) | 2009-11-10 | — | — | US | disclosed |