Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 6/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.30 |
| ▸ | CA9 | Q16790 | 3/20 | 0.30 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.30 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14228335 | 0.92 | P2RY12 (0.44) | P2RY12IMPDH2 | |
| SCHEMBL9922629 | 0.92 | P2RY12 (0.39) | P2RY12IMPDH2BRD4CREBBPCA12 | |
| SCHEMBL9922586 | 0.91 | P2RY12 (0.40) | P2RY12IMPDH2BRD4CREBBPCA12 | |
| SCHEMBL9923020 | 0.88 | P2RY12 (0.41) | P2RY12IMPDH2BRD4CREBBPCA12 | |
| SCHEMBL12160988 | 0.86 | P2RY12 (0.45) | P2RY12IMPDH2CA12CA9CA1 | |
| SCHEMBL14228642 | 0.84 | P2RY12 (0.35) | P2RY12BRD4CREBBP | |
| SCHEMBL9922050 | 0.84 | P2RY12 (0.36) | P2RY12IMPDH2BRD4CREBBPCA12 | |
| SCHEMBL13638625 | 0.83 | P2RY12 (0.47) | P2RY12CA12CA9KCNA1KCNAB1 | |
| SCHEMBL12160875 | 0.83 | P2RY12 (0.49) | P2RY12IMPDH2 | |
| SCHEMBL9922630 | 0.82 | P2RY12 (0.42) | P2RY12BRD4CREBBPCA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622474-B2 | Asulfonyl(urea, thiourea, guanidine, cyanoguanidine) compounds; cardiovascular disorders; thrombosis | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-11-24 | — | — | US | disclosed |