Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14113568 | 0.93 | RPS6KB1 (0.33) | RPS6KB1 | |
| SCHEMBL12177072 | 0.85 | CA12 (0.35) | SMN1; SMN2MAPTKMT2A | |
| SCHEMBL9922633 | 0.84 | SMN1; SMN2 (0.36) | RPS6KB1SMN1; SMN2MEN1GAAMAPT | |
| SCHEMBL12160993 | 0.84 | P2RY12 (0.41) | RPS6KB1SMN1; SMN2MEN1GAAMAPT | |
| SCHEMBL12177104 | 0.80 | RPS6KB1 (0.32) | RPS6KB1MCHR1 | |
| SCHEMBL12177071 | 0.79 | P2RY12 (0.41) | RPS6KB1SMN1; SMN2MEN1GAAMAPT | |
| SCHEMBL12160884 | 0.78 | P2RY12 (0.45) | RPS6KB1SMN1; SMN2MEN1GAAMAPT | |
| SCHEMBL9922283 | 0.76 | P2RY12 (0.37) | RPS6KB1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL14200753 | 0.76 | MAPT (0.39) | RPS6KB1SMN1; SMN2MEN1GAAMAPT | |
| SCHEMBL9922208 | 0.76 | MEN1 (0.36) | RPS6KB1MEN1MAPTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622474-B2 | Asulfonyl(urea, thiourea, guanidine, cyanoguanidine) compounds; cardiovascular disorders; thrombosis | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-11-24 | — | — | US | disclosed |