Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12160993 | 0.94 | P2RY12 (0.41) | SMN1; SMN2LMNAL3MBTL1P2RY12RPS6KB1 | |
| SCHEMBL9922283 | 0.92 | P2RY12 (0.37) | SMN1; SMN2LMNAL3MBTL1P2RY12RPS6KB1 | |
| SCHEMBL14113601 | 0.89 | P2RY12 (0.38) | SMN1; SMN2P2RY12RPS6KB1KMT2AMEN1 | |
| SCHEMBL12177071 | 0.89 | P2RY12 (0.41) | SMN1; SMN2LMNAL3MBTL1P2RY12RPS6KB1 | |
| SCHEMBL12160884 | 0.88 | P2RY12 (0.45) | SMN1; SMN2LMNAL3MBTL1P2RY12RPS6KB1 | |
| SCHEMBL9922047 | 0.86 | RPS6KB1 (0.35) | SMN1; SMN2LMNAL3MBTL1P2RY12RPS6KB1 | |
| SCHEMBL9922426 | 0.85 | P2RY12 (0.38) | P2RY12CA12CA1CA9 | |
| SCHEMBL9922463 | 0.85 | P2RY12 (0.46) | SMN1; SMN2LMNAP2RY12RPS6KB1KMT2A | |
| SCHEMBL9922630 | 0.85 | P2RY12 (0.42) | SMN1; SMN2LMNAP2RY12KMT2AMEN1 | |
| SCHEMBL13638626 | 0.84 | RPS6KB1 (0.34) | SMN1; SMN2LMNAL3MBTL1RPS6KB1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149688-A1 | PLATELET ADP RECEPTOR INHIBITORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149688-A1 | PLATELET ADP RECEPTOR INHIBITORS | TBXA2R, GP6, P2RY6 | SMN1; SMN2 3093/4885LMNA 3603/4885L3MBTL1 4538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.