Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
| ▸ | FBP1 | P09467 | 8/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | GHSR | Q92847 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9922987 | 0.93 | P2RY12 (0.42) | P2RY12FBP1MEN1KMT2APIK3CA | |
| SCHEMBL12177246 | 0.88 | PIK3CA (0.34) | P2RY12FBP1MEN1USP2KMT2A | |
| SCHEMBL9923274 | 0.82 | P2RY12 (0.41) | P2RY12FBP1MEN1KMT2APIK3CA | |
| SCHEMBL13638637 | 0.81 | P2RY12 (0.36) | P2RY12FBP1MEN1KMT2AKIT | |
| SCHEMBL13638638 | 0.78 | P2RY12 (0.38) | P2RY12FBP1MEN1KMT2ACREBBP | |
| SCHEMBL13638632 | 0.78 | P2RY12 (0.42) | P2RY12MEN1KMT2AKITCREBBP | |
| SCHEMBL9923177 | 0.76 | P2RY12 (0.55) | P2RY12FBP1MEN1KMT2AKIT | |
| SCHEMBL9922690 | 0.75 | P2RY12 (0.46) | P2RY12FBP1MEN1KMT2A | |
| SCHEMBL13638377 | 0.75 | P2RY12 (0.42) | P2RY12FBP1CREBBP | |
| SCHEMBL9922537 | 0.74 | P2RY12 (0.45) | P2RY12FBP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622474-B2 | Asulfonyl(urea, thiourea, guanidine, cyanoguanidine) compounds; cardiovascular disorders; thrombosis | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-11-24 | — | — | US | disclosed |