Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | KIT | P10721 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9922859 | 0.93 | P2RY12 (0.55) | P2RY12KMT2AMEN1MAPTRXFP1 | |
| SCHEMBL9922446 | 0.89 | P2RY12 (0.53) | P2RY12KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL12177250 | 0.88 | P2RY12 (0.58) | P2RY12KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL12706582 | 0.86 | P2RY12 (0.46) | P2RY12KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL12177332 | 0.85 | KMT2A (0.39) | P2RY12KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL9922096 | 0.85 | P2RY12 (0.47) | P2RY12KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13638699 | 0.85 | P2RY12 (0.47) | P2RY12KMT2AMEN1RXFP1KIT | |
| SCHEMBL14113676 | 0.84 | P2RY12 (0.48) | P2RY12KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9922100 | 0.83 | P2RY12 (0.48) | P2RY12KMT2AMEN1KITERCC1 | |
| SCHEMBL9922647 | 0.82 | P2RY12 (0.69) | P2RY12KMT2AMEN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622474-B2 | Asulfonyl(urea, thiourea, guanidine, cyanoguanidine) compounds; cardiovascular disorders; thrombosis | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-11-24 | — | — | US | disclosed |