Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPD | P32754 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9923200 | 0.93 | P2RY12 (0.49) | P2RY12GLANOD1RAB9APPARG | |
| SCHEMBL12177329 | 0.89 | P2RY12 (0.41) | P2RY12GLANOD1RAB9APPARG | |
| SCHEMBL12177247 | 0.89 | GLA (0.52) | P2RY12GLANOD1PPARGHPD | |
| SCHEMBL14113579 | 0.88 | P2RY12 (0.39) | P2RY12GLANOD1PPARGMEN1 | |
| SCHEMBL13638511 | 0.88 | P2RY12 (0.45) | P2RY12NOD1RAB9APPARGRXFP1 | |
| SCHEMBL12177248 | 0.87 | P2RY12 (0.40) | P2RY12GLANOD1RAB9AMEN1 | |
| SCHEMBL9923210 | 0.87 | P2RY12 (0.40) | P2RY12GLANOD1PPARGMEN1 | |
| SCHEMBL13638586 | 0.87 | P2RY12 (0.40) | P2RY12GLANOD1RAB9APPARG | |
| SCHEMBL13638710 | 0.86 | P2RY12 (0.40) | P2RY12GLANOD1RAB9APPARG | |
| SCHEMBL9923204 | 0.85 | P2RY12 (0.41) | P2RY12GLANOD1RAB9APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622474-B2 | Asulfonyl(urea, thiourea, guanidine, cyanoguanidine) compounds; cardiovascular disorders; thrombosis | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-11-24 | — | — | US | disclosed |