Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13639000 | 0.95 | KMT2A (0.41) | KMT2AMAPTTSHRACKR3OPRK1 | |
| SCHEMBL2771912 | 0.95 | KMT2A (0.41) | KMT2AMAPTTSHRACKR3OPRK1 | |
| SCHEMBL13634766 | 0.94 | KMT2A (0.41) | KMT2AMAPTTSHROPRK1F10 | |
| SCHEMBL13164103 | 0.92 | ACKR3 (0.36) | KMT2AACKR3OPRK1 | |
| SCHEMBL13638912 | 0.91 | KMT2A (0.47) | KMT2AMAPTTSHROPRK1F10 | |
| SCHEMBL13638919 | 0.90 | KMT2A (0.38) | KMT2AACKR3OPRK1ARIRAK4 | |
| SCHEMBL13270640 | 0.89 | F10 (0.40) | KMT2AMAPTTSHROPRK1F10 | |
| SCHEMBL13634734 | 0.89 | KMT2A (0.41) | KMT2AMAPTTSHROPRK1F10 | |
| SCHEMBL13634758 | 0.89 | KMT2A (0.41) | KMT2AMAPTTSHROPRK1F10 | |
| SCHEMBL13270655 | 0.89 | ACHE (0.41) | KMT2AMAPTTSHROPRK1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |