Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 11/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | SCD | O00767 | 2/20 | 0.35 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13639001 | 0.92 | KMT2A (0.38) | DRD4GRM2KMT2ASCDSCD5 | |
| SCHEMBL2770243 | 0.92 | KMT2A (0.38) | DRD4GRM2KMT2ASCDSCD5 | |
| SCHEMBL13638912 | 0.91 | KMT2A (0.47) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL13638951 | 0.90 | PDCD1 (0.40) | GRM2KMT2ASCDSCD5 | |
| SCHEMBL13634725 | 0.90 | DRD4 (0.46) | DRD4GRM2KMT2ASIGMAR1SCD | |
| SCHEMBL13638818 | 0.90 | DRD4 (0.41) | DRD4GRM2KMT2ASIGMAR1 | |
| SCHEMBL13638823 | 0.90 | DRD4 (0.41) | DRD4GRM2KMT2ASIGMAR1 | |
| Fumaric Acid SCHEMBL2771644 | 0.89 | CCKAR (0.36) | DRD4GRM2KMT2ASCDSCD5 | |
| Fumaric Acid SCHEMBL2771640 | 0.89 | CCKAR (0.36) | DRD4GRM2KMT2ASCDSCD5 | |
| SCHEMBL2770055 | 0.88 | PARP1 (0.38) | KMT2ASCDSCD5CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |