Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638747 | 0.82 | HRH3 (0.40) | HRH3HRH4NPC1RAB9APDE1B | |
| SCHEMBL7222772 | 0.78 | HRH3 (0.51) | HRH3HRH4NPC1RAB9APDE1B | |
| SCHEMBL313877 | 0.76 | HRH3 (0.51) | HRH3HRH4NPC1RAB9ACCR2 | |
| SCHEMBL13162813 | 0.76 | ALDH1A1 (0.54) | PDE1BCCR2ALDH1A1HDAC1PARP1 | |
| SCHEMBL31428702 | 0.76 | NPC1 (0.39) | HRH3HRH4NPC1RAB9APDE1B | |
| Hydrochloric Acid SCHEMBL7221627 | 0.75 | HRH3 (0.50) | HRH3HRH4NPC1RAB9ACCR2 | |
| Hydrochloric Acid SCHEMBL6340964 | 0.75 | HRH3 (0.50) | HRH3HRH4NPC1RAB9ACCR2 | |
| SCHEMBL3086988 | 0.74 | NPC1 (0.44) | HRH3HRH4NPC1RAB9ALMNA | |
| SCHEMBL3094208 | 0.73 | HRH3 (0.51) | HRH3HRH4NPC1RAB9APDE1B | |
| SCHEMBL16193406 | 0.71 | HRH3 (0.53) | HRH3HRH4NPC1RAB9APDE1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |