Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.70 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.53 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.53 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3456168 | 0.83 | HSD17B10 (0.66) | HSD17B10HPGDALDH1A1KDM4ETSHR | |
| SCHEMBL3705934 | 0.79 | HTT (0.63) | HSD17B10HPGDALDH1A1KDM4ETSHR | |
| SCHEMBL13634586 | 0.79 | NPC1 (0.56) | HPGDNPC1RAB9ACNR2SMN1; SMN2 | |
| SCHEMBL13193072 | 0.79 | NPC1 (0.59) | HPGDALDH1A1NPC1RAB9ATAS1R3 | |
| SCHEMBL15983801 | 0.79 | NPC1 (0.73) | HSD17B10HPGDALDH1A1TSHRNPC1 | |
| SCHEMBL6356632 | 0.78 | P2RX7 (0.61) | HSD17B10HPGDALDH1A1KDM4ETSHR | |
| Hydrochloric Acid SCHEMBL11301487 | 0.78 | HTT (0.61) | HSD17B10HPGDALDH1A1KDM4ETSHR | |
| SCHEMBL15271409 | 0.77 | NPC1 (0.58) | HPGDALDH1A1NPC1RAB9ATAS1R3 | |
| SCHEMBL16018368 | 0.77 | NPC1 (0.58) | HPGDALDH1A1NPC1RAB9ATAS1R3 | |
| SCHEMBL27544844 | 0.77 | NPC1 (0.58) | HPGDALDH1A1NPC1RAB9ATAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206707-B1 | AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2014-07-23 | — | — | EP | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |