Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 5/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | PHGDH | O43175 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638858 | 0.84 | KMT2A (0.52) | ERN1HPGDKMT2APOLBALDH1A1 | |
| SCHEMBL17345591 | 0.78 | HPGD (0.63) | ERN1PKMHPGDPHGDHHSP90AA1 | |
| SCHEMBL1911937 | 0.77 | KMT2A (0.64) | PKMHPGDKMT2AGLAPOLB | |
| SCHEMBL6223848 | 0.77 | ERN1 (0.56) | ERN1PKMHPGDPHGDHHSP90AA1 | |
| SCHEMBL20954371 | 0.75 | ERN1 (0.50) | ERN1PKMHPGDPHGDHHSP90AA1 | |
| SCHEMBL10720943 | 0.74 | PHGDH (0.81) | PKMHPGDPHGDHKMT2APOLB | |
| SCHEMBL1662915 | 0.73 | PHGDH (0.65) | ERN1PKMHPGDPHGDHKMT2A | |
| SCHEMBL31429067 | 0.73 | ALDH1A1 (0.57) | ERN1PKMHPGDPHGDHALDH1A1 | |
| SCHEMBL28114856 | 0.73 | ALDH1A1 (0.57) | ERN1PKMHPGDPHGDHALDH1A1 | |
| SCHEMBL17443637 | 0.73 | HRH3 (0.56) | ERN1PKMHPGDPHGDHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |