Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | SMO | Q99835 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638795 | 0.92 | IRAK4 (0.35) | GPR119ALOX5APIRAK4PIM1 | |
| SCHEMBL13638797 | 0.87 | — | — | |
| SCHEMBL13162780 | 0.85 | — | — | |
| SCHEMBL13162782 | 0.85 | ITGB2 (0.31) | — | |
| SCHEMBL13162324 | 0.82 | AR (0.35) | KDM4EALDH1A1SMN1; SMN2IRAK4 | |
| SCHEMBL13162786 | 0.82 | EGFR (0.31) | — | |
| SCHEMBL13162781 | 0.82 | CHRM3 (0.31) | — | |
| SCHEMBL13638964 | 0.79 | AOC3 (0.33) | — | |
| SCHEMBL13162801 | 0.78 | GPR119 (0.34) | GPR119 | |
| SCHEMBL13162326 | 0.77 | OGA (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |