Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.30 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL318778 | 0.80 | LMNA (0.50) | RECQLKDM4E | |
| SCHEMBL318779 | 0.80 | LMNA (0.50) | RECQLKDM4E | |
| SCHEMBL10087007 | 0.71 | — | — | |
| Methacrylic Acid SCHEMBL28134789 | 0.68 | LMNA (0.42) | KDM4EGRIK1GRIK2 | |
| SCHEMBL28396306 | 0.68 | GRIK1 (0.48) | KDM4EGRIK1GRIK2 | |
| SCHEMBL3151120 | 0.67 | CES1 (0.50) | — | |
| SCHEMBL2946248 | 0.67 | CES1 (0.50) | — | |
| SCHEMBL2946250 | 0.67 | CES1 (0.50) | — | |
| SCHEMBL12872174 | 0.66 | — | — | |
| SCHEMBL21237879 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8303935-B2 | Alkoxy substituted imidazo[1,2-a]pyridines having affinity for amyloid | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2012-11-06 | — | — | US | disclosed |