Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 6/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13639143 | 0.93 | PTGER4 (0.37) | PTGER3PTGER4PTGER2MEN1KMT2A | |
| SCHEMBL14304030 | 0.71 | — | — | |
| SCHEMBL27904162 | 0.70 | PTGER4 (0.47) | PTGER3PTGER4PTGER2MEN1KMT2A | |
| SCHEMBL12329805 | 0.69 | PTGER4 (0.61) | PTGER3PTGER4PTGER2PTGER1 | |
| SCHEMBL13639146 | 0.69 | PTGER4 (0.61) | PTGER3PTGER4PTGER2PTGER1 | |
| SCHEMBL13639166 | 0.69 | PTGER3 (0.58) | PTGER3PTGER4PTGER2PTGER1 | |
| SCHEMBL12329809 | 0.69 | PTGER3 (0.58) | PTGER3PTGER4PTGER2PTGER1 | |
| SCHEMBL12329882 | 0.68 | DAO (0.45) | PTGER3PTGER4PTGER2PTGER1 | |
| SCHEMBL12329795 | 0.67 | PTGER4 (0.41) | PTGER3PTGER4PTGER2 | |
| SCHEMBL26744978 | 0.67 | PER2 (0.41) | PTGER3PTGER4PTGER2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481976-B1 | 8-AZAPROSTAGLANDIN DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2012-11-07 | — | — | EP | disclosed |