Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6 | P05231 | 6/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | FPR1 | P21462 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4135649 | 0.87 | IL6 (0.48) | IL6LMNATP53MAPTHTT | |
| SCHEMBL1780249 | 0.85 | MAPT (0.42) | LMNATP53MAPTHTTNPSR1 | |
| SCHEMBL1918849 | 0.84 | IL6 (0.37) | IL6LMNA | |
| SCHEMBL4581249 | 0.82 | IL6 (0.41) | IL6LMNA | |
| SCHEMBL14878811 | 0.82 | IL6 (0.36) | IL6KMT2A | |
| SCHEMBL4581943 | 0.80 | IL6 (0.33) | IL6LMNAMAPTKMT2A | |
| SCHEMBL4135970 | 0.79 | IL6 (0.43) | IL6LMNAMAPTGAAKMT2A | |
| SCHEMBL4140091 | 0.78 | IL6 (0.47) | IL6LMNATP53MAPTHTT | |
| SCHEMBL13571961 | 0.77 | IL6 (0.47) | IL6LMNA | |
| SCHEMBL1782536 | 0.76 | MAPT (0.57) | LMNATP53MAPTHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1995242-B1 | NOVEL 1,2,3,4-TETRAHYDROQUINOXALINE DERIVATIVE HAVING GLUCOCORTICOID RECEPTOR BINDING ACTIVITY | SANTEN PHARMACEUTICAL CO LTD (JP) | 2012-11-07 | — | — | EP | disclosed |