Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 17/20 | 0.76 |
| ▸ | S100A9 | P06702 | 2/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3785151 | 0.86 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL3771867 | 0.84 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL13768257 | 0.84 | PTGES2 (0.59) | PTGES2S100A9 | |
| SCHEMBL13639450 | 0.72 | PTGES2 (0.52) | PTGES2SLC22A12 | |
| SCHEMBL13061971 | 0.71 | PTGES2 (0.80) | PTGES2 | |
| SCHEMBL3786218 | 0.70 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL3778116 | 0.70 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL13012078 | 0.68 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL3783279 | 0.68 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL3782877 | 0.67 | PTGES2 (1.00) | PTGES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2234993-B1 | BIS- (SULF ONYLAMINO) DERIVATIVES FOR USE IN THERAPY | ASTRAZENECA AB (SE) | 2012-11-07 | — | — | EP | disclosed |