Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 18/20 | 0.52 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3778023 | 0.86 | PTGES2 (0.71) | PTGES2 | |
| SCHEMBL3778029 | 0.86 | PTGES2 (0.71) | PTGES2 | |
| SCHEMBL3774927 | 0.84 | PTGES2 (0.71) | PTGES2 | |
| SCHEMBL3774933 | 0.84 | PTGES2 (0.71) | PTGES2 | |
| SCHEMBL13768481 | 0.84 | PTGES2 (0.57) | PTGES2 | |
| SCHEMBL13639444 | 0.72 | PTGES2 (0.76) | PTGES2SLC22A12 | |
| SCHEMBL13062159 | 0.71 | PTGES2 (0.77) | PTGES2 | |
| SCHEMBL3782945 | 0.70 | PTGES2 (0.78) | PTGES2 | |
| SCHEMBL3779099 | 0.70 | PTGES2 (0.78) | PTGES2 | |
| SCHEMBL3779094 | 0.70 | PTGES2 (0.78) | PTGES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2234993-B1 | BIS- (SULF ONYLAMINO) DERIVATIVES FOR USE IN THERAPY | ASTRAZENECA AB (SE) | 2012-11-07 | — | — | EP | disclosed |