Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 4/20 | 0.55 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL718782 | 0.85 | GCK (0.72) | GCKLNPEPPTGESALOX5PPARG | |
| SCHEMBL12020984 | 0.74 | GCK (0.62) | GCKLNPEPPTGESALOX5PPARG | |
| SCHEMBL9072543 | 0.74 | GCK (0.62) | GCKLNPEPPTGESALOX5PPARG | |
| SCHEMBL2668261 | 0.74 | MEN1 (0.70) | GCKKMT2AMEN1 | |
| SCHEMBL2657438 | 0.74 | GCK (0.64) | GCKLNPEPPTGESALOX5PPARG | |
| SCHEMBL14018725 | 0.72 | F2 (0.49) | GCKLNPEPPTGESALOX5PPARG | |
| SCHEMBL14017936 | 0.72 | GCK (0.59) | GCKLNPEPPTGESALOX5PPARG | |
| SCHEMBL9374246 | 0.72 | KMT2A (0.59) | KMT2A | |
| SCHEMBL14505791 | 0.71 | GCK (1.00) | GCKRARB | |
| SCHEMBL2668266 | 0.71 | KMT2A (0.50) | GCKKMT2AMEN1RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940837-B1 | IMIDAZOPYRIDINE COMPOUNDS | TAKEDA PHARMACEUTICAL (JP) | 2012-11-07 | — | — | EP | disclosed |