Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.58 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.55 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.55 |
| ▸ | MRGPRX4 | Q96LA9 | 8/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.50 |
| ▸ | RELA | Q04206 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | GCK | P35557 | 1/20 | 0.49 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2319276 | 0.88 | LMNA (0.58) | MEN1KMT2ANR4A2NR4A1NR4A3 | |
| SCHEMBL27812422 | 0.85 | MEN1 (0.68) | MEN1KMT2ANR4A2NR4A1NR4A3 | |
| SCHEMBL13228336 | 0.84 | MAOB (0.53) | MEN1KMT2AMAOBSMN1; SMN2RAB9A | |
| SCHEMBL862870 | 0.83 | MEN1 (0.93) | MEN1KMT2ANR4A2NR4A1NR4A3 | |
| SCHEMBL1426961 | 0.83 | MEN1 (1.00) | MEN1KMT2ANR4A2NR4A1NR4A3 | |
| SCHEMBL15580330 | 0.83 | MEN1 (0.47) | MEN1KMT2ANR4A2MAOBGCK | |
| SCHEMBL10200052 | 0.82 | MEN1 (0.79) | MEN1KMT2ANR4A2NR4A1NR4A3 | |
| SCHEMBL11693918 | 0.82 | MEN1 (0.60) | MEN1KMT2ANR4A2NR4A1NR4A3 | |
| SCHEMBL2666120 | 0.82 | MEN1 (0.73) | MEN1KMT2ANR4A2NR4A1NR4A3 | |
| SCHEMBL9368673 | 0.82 | MRGPRX4 (0.69) | NR4A2MRGPRX4SMN1; SMN2TP53PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940837-B1 | IMIDAZOPYRIDINE COMPOUNDS | TAKEDA PHARMACEUTICAL (JP) | 2012-11-07 | — | — | EP | disclosed |
| WO-2007028135-A2 | IMIDAZOPYRIDINE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-03-08 | — | — | WO | disclosed |