Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GCK | P35557 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL999793 | 0.87 | SMN1; SMN2 (0.43) | GCK | |
| SCHEMBL998535 | 0.86 | SMN1; SMN2 (0.40) | — | |
| SCHEMBL999458 | 0.85 | SMN1; SMN2 (0.43) | GCK | |
| SCHEMBL1002043 | 0.84 | ALDH1A1 (0.41) | GCK | |
| SCHEMBL999243 | 0.83 | SMN1; SMN2 (0.39) | GCK | |
| SCHEMBL999241 | 0.83 | SMN1; SMN2 (0.39) | GCK | |
| SCHEMBL999866 | 0.83 | MAPT (0.41) | — | |
| SCHEMBL1002171 | 0.82 | SMN1; SMN2 (0.38) | GCK | |
| SCHEMBL996578 | 0.81 | MAPT (0.39) | GCK | |
| SCHEMBL999341 | 0.81 | MAPT (0.39) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1723128-B1 | HETEROARYL-UREAS AND THEIR USE AS GLUCOKINASE ACTIVATORS | NOVO NORDISK AS (DK) | 2012-11-07 | — | — | EP | disclosed |