Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18179232 | 0.72 | — | — | |
| SCHEMBL15849949 | 0.72 | — | — | |
| SCHEMBL6253196 | 0.71 | — | — | |
| SCHEMBL6253198 | 0.71 | — | — | |
| SCHEMBL12934284 | 0.71 | — | — | |
| SCHEMBL6887821 | 0.70 | — | — | |
| SCHEMBL25626689 | 0.70 | — | — | |
| SCHEMBL19676753 | 0.70 | — | — | |
| SCHEMBL13856187 | 0.69 | — | — | |
| SCHEMBL15933364 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9650360-B2 | Anti-mycobacterial drugs against tuberculosis | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2017-05-16 | — | — | US | disclosed |
| US-9650360-B2 | Anti-mycobacterial drugs against tuberculosis | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2017-05-16 | — | — | US | disclosed |
| EP-2831056-B1 | NEW ANTI-MYCOBACTERIAL DRUGS AGAINST TUBERCULOSIS | THE UNIV OF GEORGIA RES FOUND INC (US) | 2016-12-14 | — | — | EP | disclosed |
| US-20150050237-A1 | NEW ANTI-MYCOBACTERIAL DRUGS AGAINST TUBERCULOSIS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-02-19 | — | — | US | disclosed |
| US-8703801-B2 | Pyridinone hydroxycyclopentyl carboxamides: HIV integrase inhibitors with therapeutic applications | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2014-04-22 | — | — | US | disclosed |
| WO-2013148174-A1 | NEW ANTI-MYCOBACTERIAL DRUGS AGAINST TUBERCULOSIS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2013-10-03 | — | — | WO | disclosed |
| US-20120282218-A1 | PYRIDINONE HYDROXYCYCLOPENTYL CARBOXAMIDES: HIV INTEGRASE INHIBITORS WITH THERAPEUTIC APPLICATIONS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION INC. (US) | 2012-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120282218-A1 | PYRIDINONE HYDROXYCYCLOPENTYL CARBOXAMIDES: HIV INTEGRASE INHIBITORS WITH THERAPEUTIC APPLICATIONS | PAICS, DUT, AADAC | ALDH1A1 2717/4885FFAR3 4204/4885LCK 156/4885 |
| US-20150050237-A1 | NEW ANTI-MYCOBACTERIAL DRUGS AGAINST TUBERCULOSIS | FNTB, ABCC1, TBCD | ALDH1A1 3146/4885FFAR3 3542/4885LCK 2152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.