Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HMGCR | P04035 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15314352 | 0.82 | BCL2 (0.54) | PKMHSP90AB1CA1CA2GAA | |
| SCHEMBL27658629 | 0.80 | KDM4E (0.47) | CA1CA2KDM4EMAPTGAA | |
| SCHEMBL13640224 | 0.80 | GAA (0.46) | CA1CA2GAAHTTBCL2 | |
| Benzene SCHEMBL9247233 | 0.79 | BCL2 (0.46) | CA1CA2KDM4EMAPTHSD17B10 | |
| SCHEMBL30576398 | 0.78 | NR2F2 (0.53) | HSP90AB1KDM4EMAPTUBE2NHSD17B10 | |
| SCHEMBL8812760 | 0.78 | NR2F2 (0.53) | HSP90AB1KDM4EMAPTUBE2NHSD17B10 | |
| SCHEMBL13640203 | 0.78 | CA1 (0.38) | PKMCA1CA2MAPTGAA | |
| SCHEMBL11559830 | 0.77 | HMGB1 (0.46) | HSP90AB1KDM4EMAPTUBE2NHSD17B10 | |
| SCHEMBL24912687 | 0.75 | PLAU (0.43) | HSP90AB1KDM4EMAPTUBE2NHSD17B10 | |
| SCHEMBL30307562 | 0.75 | PLAU (0.43) | HSP90AB1KDM4EMAPTUBE2NHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120283335-A1 | Analogs of Propofol, Preparation Thereof and Use as Anesthetics | SIGNATURE THERAPEUTICS, INC. | 2012-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120283335-A1 | Analogs of Propofol, Preparation Thereof and Use as Anesthetics | GABRP, CYP4F11, CYP2F1 | PKM 1091/4885HSP90AB1 2164/4885CA1 2438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.