Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL678189 | 0.90 | ALOX12 (0.65) | PTPN1ALOX12CYP19A1ALOX15MEN1 | |
| SCHEMBL29412620 | 0.90 | ALOX12 (0.65) | PTPN1ALOX12CYP19A1ALOX15MEN1 | |
| SCHEMBL12825176 | 0.90 | ALOX12 (0.65) | PTPN1ALOX12CYP19A1ALOX15MEN1 | |
| SCHEMBL14281987 | 0.89 | CYP19A1 (0.53) | PTPN1ALOX12CYP19A1ALOX15MEN1 | |
| SCHEMBL13923932 | 0.89 | CYP19A1 (0.53) | PTPN1ALOX12CYP19A1ALOX15MEN1 | |
| SCHEMBL15070036 | 0.86 | ALOX12 (0.60) | PTPN1ALOX12CYP19A1ALOX15MEN1 | |
| SCHEMBL2850735 | 0.86 | CYP19A1 (0.54) | PTPN1ALOX12CYP19A1ALOX15MEN1 | |
| Dihydrobiochanin A SCHEMBL30217535 | 0.86 | ALOX12 (0.67) | PTPN1ALOX12CYP19A1ALOX15MEN1 | |
| SCHEMBL30217542 | 0.85 | PTPN1 (0.57) | PTPN1ALOX12CYP19A1ALOX15MEN1 | |
| SCHEMBL17963719 | 0.85 | PTPN1 (0.57) | PTPN1ALOX12CYP19A1ALOX15MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120283313-A1 | INHIBITION AND TREATMENT OF PROSTATE CANCER METASTASIS | NORTHWESTERN UNIVERSITY (US) | 2012-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120283313-A1 | INHIBITION AND TREATMENT OF PROSTATE CANCER METASTASIS | MAPK4, MAP4K4, MAP3K4 | PTPN1 2190/4885ALOX12 3543/4885CYP19A1 705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.