Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 1.00 |
| ▸ | HPGD | P15428 | 4/20 | 1.00 |
| ▸ | USP2 | O75604 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | BACE1 | P56817 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.53 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.53 |
| ▸ | GGT1 | P19440 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CFD | P00746 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triflusal SCHEMBL29435450 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10HPGDUSP2 | |
| Triflusal SCHEMBL29435449 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10HPGDUSP2 | |
| Triflusal SCHEMBL4960641 | 0.98 | KDM4E (0.97) | KDM4EALDH1A1HSD17B10HPGDUSP2 | |
| Triflusal SCHEMBL2322418 | 0.92 | KDM4E (0.84) | KDM4EALDH1A1HSD17B10HPGDUSP2 | |
| SCHEMBL18623999 | 0.89 | KDM4E (0.80) | KDM4EALDH1A1HSD17B10HPGDUSP2 | |
| SCHEMBL15684623 | 0.89 | KDM4E (0.79) | KDM4EALDH1A1HSD17B10HPGDUSP2 | |
| SCHEMBL4307017 | 0.88 | KDM4E (0.78) | KDM4EALDH1A1HSD17B10HPGDUSP2 | |
| SCHEMBL27781530 | 0.87 | KDM4E (0.77) | KDM4EALDH1A1HSD17B10HPGDUSP2 | |
| SCHEMBL3056059 | 0.86 | KDM4E (0.75) | KDM4EALDH1A1HSD17B10HPGDUSP2 | |
| SCHEMBL15743761 | 0.86 | KDM4E (0.75) | KDM4EALDH1A1HSD17B10HPGDUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3493 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260137702-A1 | Salicylate Compound Composition | INNOVATE EU LTD (GB) | 2026-05-21 | — | — | US | claimed |
| EP-3996700-B1 | TREATMENT OF PATIENTS UNDER ANTIPLATELET MEDICATION EXPERIENCING BLEEDING | FAELKER KNUT (SE) | 2026-04-29 | — | — | EP | claimed |
| US-12521258-B2 | Anticoagulant compounds and methods and devices for their use | ELIXIR MEDICAL CORPORATION (US) | 2026-01-13 | — | — | US | claimed |
| US-20250388639-A1 | Therapeutic applications based on the inhibition of G Protein-Coupled Receptor 182 (GPR182) | MAX PLANCK GESELLSCHAFT (DE) | 2025-12-25 | — | — | US | claimed |
| US-20250381156-A1 | TREATMENT OR PREVENTION OF CARDIOVASCULAR EVENTS VIA THE ADMINISTRATION OF A COLCHICINE DERIVATIVE | MURRAY AND POOLE ENTPR LTD (GI) | 2025-12-18 | — | — | US | claimed |
| EP-4547331-A1 | THERAPEUTIC APPLICATIONS BASED ON THE INHIBITION OF G PROTEIN-COUPLED RECEPTOR 182 (GPR182) | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2025-05-07 | — | — | EP | claimed |
| US-12233035-B2 | Method of treating cardiovascular events using colchicine concurrently with an antiplatelet agent and statin | HEART CARE WESTERN AUSTRALIA PTY LIMITED (AU) | 2025-02-25 | — | — | US | claimed |
| US-20240216380-A1 | BTK Inhibitors to Treat Solid Tumors Through Modulation of the Tumor Microenvironment | ACERTA PHARMA BV (NL) | 2024-07-04 | — | — | US | claimed |
| US-20240180904-A1 | Methods of Treating Chronic Lymphocytic Leukemia and Small Lymphocytic Leukemia Using a BTK Inhibitor | ACERTA PHARMA BV (NL) | 2024-06-06 | — | — | US | claimed |
| US-20240034752-A1 | ARTIFICIAL SHORT INTERFERING PEPTIDE FOR THE PHOSPHORYLATION SUBSTRATE OF DAPK1 AND ITS PHARMACEUTICAL APPLICATIONS | BEIJING SINANCHENG TECHNOLOGY CO., LTD. (CN) | 2024-02-01 | — | — | US | claimed |
| WO-2000061549-A2 | PHARMACEUTICAL COMPOUNDS | NICOX S.A. (FR) | 2000-10-19 | — | — | WO | claimed |
| WO-2000061541-A2 | PHARMACEUTICAL COMPOUNDS | NICOX S.A. (FR) | 2000-10-19 | — | — | WO | claimed |
| WO-2000061537-A2 | PHARMACEUTICAL COMPOUNDS | NICOX S.A. (FR) | 2000-10-19 | — | — | WO | claimed |
| WO-2000048636-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS | INPHARMA S.A. (CH) | 2000-08-24 | — | — | WO | claimed |
| WO-2000012076-A9 | NITROSATED AND NITROSYLATED PHOSPHODIESTERASE INHIBITORS, COMPOSITIONS AND METHODS OF USE | NITROMED INC (US) | 2000-08-17 | — | — | WO | claimed |
| EP-0985413-A1 | Medical articles with sustained pharmacological activity and process for their preparation | Schierholz, Jörg Michael, Dr. Dr. (DE) | 2000-03-15 | — | — | EP | claimed |
| WO-2000012076-A1 | NITROSATED AND NITROSYLATED PHOSPHODIESTERASE INHIBITORS, COMPOSITIONS AND METHODS OF USE | NITROMED, INC. (US) | 2000-03-09 | — | — | WO | claimed |
| WO-2000007574-A1 | MEDICINAL PRODUCTS WITH RETARDED PHARMACOLOGICAL ACTIVITY AND METHOD FOR THE PRODUCTION THEREOF | SCHIERHOLZ JOERG (DE) | 2000-02-17 | — | — | WO | claimed |
| WO-1998022114-A1 | A METHOD FOR PROMOTING TISSUE REPAIR | DUMEX-ALPHARMA A/S (DK) | 1998-05-28 | — | — | WO | claimed |
| US-4096252-A | THERAPY AND PROPHYLAXIS | J. URIACH & CIA S.A. (ES) | 1978-06-20 | — | — | US | claimed |