Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 3/20 | 0.56 |
| ▸ | SHBG | P04278 | 3/20 | 0.46 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GUSB | P08236 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 8/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13642708 | 1.00 | G6PD (0.56) | G6PDSHBGSERPINA6CYP3A4ESR1 | |
| SCHEMBL12403266 | 0.89 | G6PD (0.70) | G6PDSHBGSERPINA6CYP3A4ESR1 | |
| SCHEMBL3670416 | 0.89 | G6PD (0.70) | G6PDSHBGSERPINA6CYP3A4ESR1 | |
| SCHEMBL13642783 | 0.89 | G6PD (0.70) | G6PDSHBGSERPINA6CYP3A4ESR1 | |
| SCHEMBL13420269 | 0.89 | G6PD (0.70) | G6PDSHBGSERPINA6CYP3A4ESR1 | |
| SCHEMBL12153536 | 0.89 | G6PD (0.70) | G6PDSHBGSERPINA6CYP3A4ESR1 | |
| SCHEMBL1126907 | 0.89 | G6PD (0.70) | G6PDSHBGSERPINA6CYP3A4ESR1 | |
| SCHEMBL1126576 | 0.89 | G6PD (0.70) | G6PDSHBGSERPINA6CYP3A4ESR1 | |
| SCHEMBL14193758 | 0.89 | G6PD (0.70) | G6PDSHBGSERPINA6CYP3A4ESR1 | |
| SCHEMBL14193756 | 0.89 | G6PD (0.70) | G6PDSHBGSERPINA6CYP3A4ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120283217-A1 | MODULATORS OF AMYLOID-BETA PRODUCTION | SATORI PHARMACEUTICALS, INC. (US) | 2012-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120283217-A1 | MODULATORS OF AMYLOID-BETA PRODUCTION | APP, BACE1, BACE2 | G6PD 1270/4885SHBG 1588/4885SERPINA6 261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.