Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 9/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | ATP1A1 | P05023 | 2/20 | 0.35 |
| ▸ | ATP1B1 | P05026 | 2/20 | 0.35 |
| ▸ | ATP1A3 | P13637 | 2/20 | 0.35 |
| ▸ | ATP1B2 | P14415 | 2/20 | 0.35 |
| ▸ | ATP1A2 | P50993 | 2/20 | 0.35 |
| ▸ | ATP1B3 | P54709 | 2/20 | 0.35 |
| ▸ | FXYD2 | P54710 | 2/20 | 0.35 |
| ▸ | ATP1A4 | Q13733 | 2/20 | 0.35 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.35 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13642612 | 1.00 | GPBAR1 (0.43) | GPBAR1NR1H4PRKCDPTPN1ATP1A1 | |
| SCHEMBL13642514 | 1.00 | GPBAR1 (0.43) | GPBAR1NR1H4PRKCDPTPN1ATP1A1 | |
| SCHEMBL13642557 | 0.89 | GPBAR1 (0.48) | GPBAR1NR1H4PTPN1AKR1B10AKR1B1 | |
| SCHEMBL13642752 | 0.89 | GPBAR1 (0.48) | GPBAR1NR1H4PTPN1AKR1B10AKR1B1 | |
| SCHEMBL13642516 | 0.86 | GPBAR1 (0.35) | GPBAR1NR1H4PRKCD | |
| SCHEMBL13642452 | 0.86 | GPBAR1 (0.35) | GPBAR1NR1H4PRKCD | |
| SCHEMBL13420373 | 0.84 | HSD11B1 (0.43) | GPBAR1 | |
| SCHEMBL13420797 | 0.84 | HSD11B1 (0.43) | GPBAR1 | |
| SCHEMBL13420651 | 0.84 | HSD11B1 (0.43) | GPBAR1 | |
| SCHEMBL14047197 | 0.84 | HSD11B1 (0.43) | GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120283217-A1 | MODULATORS OF AMYLOID-BETA PRODUCTION | SATORI PHARMACEUTICALS, INC. (US) | 2012-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120283217-A1 | MODULATORS OF AMYLOID-BETA PRODUCTION | APP, BACE1, BACE2 | GPBAR1 1058/4885NR1H4 1400/4885PRKCD 2516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.