SCHEMBL13644147

SCHEMBL13644147

CCNCCN(C)c1ccccc1OC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 4/20 0.41
HTR1B P28222 2/20 0.40
HTR1A P08908 1/20 0.40
HTR1D P28221 1/20 0.40
HTR2A P28223 1/20 0.40
HTR1E P28566 1/20 0.40
HTR7 P34969 1/20 0.40
HTR2B P41595 1/20 0.40
HTR5A P47898 1/20 0.40
ADRB2 P07550 1/20 0.39
AOC3 Q16853 1/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
ESR1 P03372 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA4 P22748 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1132935 0.83 SLC6A2 (0.46) CHRM2HTR1BHTR1AHTR1DHTR2A
SCHEMBL9353842 0.81 CA12 (0.44) CHRM2HTR7AOC3ESR1CA12
Hydrochloric Acid SCHEMBL9350992 0.80 CA12 (0.43) CHRM2HTR7AOC3ESR1CA12
SCHEMBL24596957 0.78 HTR7 (0.50) CHRM2HTR1BHTR1AHTR1DHTR2A
SCHEMBL13504131 0.77 SLC6A4 (0.44) CHRM2HTR1BAOC3SLC6A2SLC6A4
SCHEMBL10428522 0.77 CA1 (0.48) CHRM2HTR7AOC3SLC6A2SLC6A4
SCHEMBL12609038 0.77 ESR1 (0.42) CHRM2HTR7AOC3SLC6A2SLC6A4
SCHEMBL13705869 0.76 TAAR1 (0.47) CHRM2HTR7AOC3SLC6A2SLC6A4
SCHEMBL5541296 0.76 CA1 (0.43) CHRM2HTR7AOC3SLC6A2SLC6A4
SCHEMBL15465790 0.76 MEN1 (0.49) CHRM2HTR7AOC3SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120284004-A1 INVERTEBRATE ACETYLCHOLINESTERASE INHIBITORS MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2012-11-08 US disclosed
WO-2008083038-A1 METHODS AND COMPOSITIONS FOR REPELLING ARTHROPODS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2008-07-10 WO disclosed