Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | GBA1 | P04062 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | DTYMK | P23919 | 2/20 | 0.39 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | CCNK | O75909 | 1/20 | 0.37 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1140969 | 0.85 | MET (0.43) | METCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL13645251 | 0.85 | CHRM2 (0.47) | CHRM2CHRM4CHRM1CHRM3ACHE | |
| SCHEMBL14603836 | 0.84 | MET (0.47) | METALDH1A1LMNAMAPT | |
| SCHEMBL14603814 | 0.80 | USP30 (0.46) | MET | |
| SCHEMBL3860841 | 0.79 | RXFP1 (0.42) | METCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL1231854 | 0.79 | BCHE (0.48) | CHRM2CHRM1CHRM3ALDH1A1LMNA | |
| SCHEMBL12757193 | 0.77 | MEN1 (0.45) | METALDH1A1LMNAMAPT | |
| SCHEMBL1041911 | 0.77 | MEN1 (0.45) | METALDH1A1LMNAMAPT | |
| SCHEMBL203034 | 0.77 | LATS1 (0.45) | METALDH1A1LMNAMAPT | |
| SCHEMBL3863551 | 0.75 | KDM4E (0.47) | METKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598382-B2 | Aryl substituted imidazoquinolines | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2009-10-06 | — | — | US | disclosed |