Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 12/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15088575 | 0.80 | CCR2 (0.36) | CCR2 | |
| SCHEMBL21337596 | 0.78 | CCR2 (0.33) | CCR2 | |
| SCHEMBL19892097 | 0.77 | CCR2 (0.36) | CCR2 | |
| SCHEMBL12065223 | 0.73 | CCR2 (0.38) | CCR2 | |
| SCHEMBL17208452 | 0.73 | CCR2 (0.38) | CCR2 | |
| SCHEMBL24836836 | 0.65 | KDM4E (0.34) | CCR2 | |
| SCHEMBL14155703 | 0.64 | CCR2 (0.38) | CCR2 | |
| SCHEMBL21294112 | 0.64 | GABRR1 (0.31) | — | |
| SCHEMBL8310841 | 0.64 | — | — | |
| SCHEMBL13072726 | 0.64 | CCR2 (0.38) | CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2108641-A1 | New substituted spiro[cycloalkyl-1,3'-indo]-2'(1'H)-one derivatives and their use as p38 mitogen-activated kinase inhibitors | Laboratorios Almirall, S.A. (ES) | 2009-10-14 | — | — | EP | disclosed |