SCHEMBL13645501

SCHEMBL13645501

CCCCCCCO[Si](C)(C)C(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DUT P33316 1/20 0.38
TSHR P16473 3/20 0.36
THRB P10828 2/20 0.36
MEN1 O00255 1/20 0.35
HTT P42858 1/20 0.35
KMT2A Q03164 1/20 0.35
MAPT P10636 1/20 0.35
ALDH1A1 P00352 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
LPAR3 Q9UBY5 6/20 0.34
LPAR2 Q9HBW0 5/20 0.34
CA1 P00915 5/20 0.34
CA2 P00918 5/20 0.34
CA9 Q16790 5/20 0.34
LPAR1 Q92633 2/20 0.34
NAAA Q02083 1/20 0.34
CA12 O43570 1/20 0.34
CA3 P07451 1/20 0.34
CA4 P22748 1/20 0.34
CA6 P23280 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7535856 1.00 DUT (0.38) DUTTSHRTHRBMEN1HTT
SCHEMBL8076746 1.00 DUT (0.38) DUTTSHRTHRBMEN1HTT
SCHEMBL29928092 1.00 DUT (0.38) DUTTSHRTHRBMEN1HTT
SCHEMBL27161205 1.00 DUT (0.38) DUTTSHRTHRBMEN1HTT
SCHEMBL8072599 1.00 DUT (0.38) DUTTSHRTHRBMEN1HTT
SCHEMBL9671669 1.00 DUT (0.38) DUTTSHRTHRBMEN1HTT
SCHEMBL5652054 1.00 DUT (0.38) DUTTSHRTHRBMEN1HTT
SCHEMBL18746891 1.00 DUT (0.38) DUTTSHRTHRBMEN1HTT
SCHEMBL31039441 1.00 DUT (0.38) DUTTSHRTHRBMEN1HTT
SCHEMBL622169 0.98 DUT (0.39) DUTTSHRTHRBMEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9102622-B2 Fatty acid amide hydrolase inhibitors UNIVERSITY OF CONNECTICUT (US) 2015-08-11 US disclosed
WO-2015106045-A1 PROCESSES FOR THE SYNTHESIS OF CHIRAL 1-ALKANOLS PURDUE RESEARCH FOUNDATION (US) 2015-07-16 WO disclosed
US-7598330-B2 Cross-metathesis of olefins directly substituted with an electron-withdrawing group using transition metal carbene catalysts CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2009-10-06 US disclosed