SCHEMBL13645587

SCHEMBL13645587

Ic1cc(-c2ccc3c(c2)CCC=C3)cc(-c2ccc3ccccc3c2)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
ALOX5 P09917 1/20 0.34
HSD17B1 P14061 1/20 0.33
HSD17B2 P37059 1/20 0.33
CYP17A1 P05093 1/20 0.32
CYP19A1 P11511 1/20 0.32
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32
GSTP1 P09211 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
FFAR4 Q5NUL3 1/20 0.31
NISCH Q9Y2I1 1/20 0.30
ACMSD Q8TDX5 1/20 0.30
KDM4E B2RXH2 1/20 0.30
NPC1 O15118 1/20 0.30
ALDH1A1 P00352 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL30523889 0.82 ESR1 (0.39) ESR1ESR2ALOX5HSD17B1HSD17B2
SCHEMBL19917003 0.79 BACE1 (0.37) ALOX5HSD17B1HSD17B2CYP17A1CYP19A1
SCHEMBL13750457 0.78
SCHEMBL13699098 0.78 FFAR4 (0.33) CYP11B1CYP11B2FFAR4
SCHEMBL25600202 0.77 KDM4E (0.33) ESR1ESR2ALOX5CYP17A1CYP19A1
SCHEMBL13523398 0.77 ESR1 (0.54) ESR1ESR2ALOX5HSD17B1HSD17B2
SCHEMBL22070064 0.77 KDM4E (0.30) NISCHKDM4EALDH1A1SMN1; SMN2
SCHEMBL21204654 0.77 HSD17B1 (0.32) ESR1ESR2HSD17B1HSD17B2CYP17A1
SCHEMBL3420195 0.76 PARP10 (0.39) ALOX5CYP11B1CYP11B2CA9FFAR4
SCHEMBL18755100 0.74 CYP11B1 (0.49) CYP17A1CYP19A1CYP11B1CYP11B2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2108690-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2009-10-14 EP disclosed