Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | F2R | P25116 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylamine SCHEMBL27566541 | 0.84 | SMN1; SMN2 (0.52) | SMN1; SMN2RXFP1POLBGAALMNA | |
| SCHEMBL4671630 | 0.84 | SMN1; SMN2 (0.54) | SMN1; SMN2RXFP1POLBEPHB3GAA | |
| SCHEMBL14280281 | 0.84 | SMN1; SMN2 (0.54) | SMN1; SMN2RXFP1POLBGAALMNA | |
| SCHEMBL10943427 | 0.82 | SMN1; SMN2 (0.53) | SMN1; SMN2HTTRXFP1POLBEPHB3 | |
| SCHEMBL12893297 | 0.82 | SMN1; SMN2 (0.53) | SMN1; SMN2RXFP1POLBGAALMNA | |
| SCHEMBL13645618 | 0.82 | KMT2A (0.49) | RXFP1MEN1KMT2A | |
| SCHEMBL10942213 | 0.81 | SMN1; SMN2 (0.52) | SMN1; SMN2RXFP1POLBEPHB3GAA | |
| SCHEMBL14280279 | 0.81 | SLC16A3 (0.55) | SMN1; SMN2RXFP1GAALMNAF2R | |
| SCHEMBL12798767 | 0.81 | SMN1; SMN2 (0.46) | SMN1; SMN2HTTRXFP1POLBGAA | |
| SCHEMBL3863550 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598389-B2 | Silylated carboxamides | BAYER CROPSCIENCE AG (DE) | 2009-10-06 | — | — | US | disclosed |
| US-20070191454-A1 | Silylated carboxamides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191454-A1 | Silylated carboxamides | MRPL21, MRPS22, MRPS34 | SMN1; SMN2 2141/4885HTT 4455/4885RXFP1 773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.