SCHEMBL14280281

SCHEMBL14280281

CCCCc1ccccc1NC(=O)c1ccccc1C(F)(F)F

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.54
F2R P25116 1/20 0.52
SLC16A3 O15427 7/20 0.51
RXFP1 Q9HBX9 2/20 0.50
LMNA P02545 1/20 0.49
GAA P10253 1/20 0.49
GRM5 P41594 1/20 0.47
KCNK3 O14649 1/20 0.47
KCNK9 Q9NPC2 1/20 0.47
PLK1 P53350 1/20 0.47
PLK3 Q9H4B4 1/20 0.47
POLB P06746 2/20 0.46
ALDH1A1 P00352 2/20 0.46
MAPK1 P28482 1/20 0.46
ALOX12 P18054 1/20 0.45
DDX3X O00571 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylamine SCHEMBL27566541 0.97 SMN1; SMN2 (0.52) SMN1; SMN2F2RSLC16A3RXFP1LMNA
SCHEMBL14280279 0.95 SLC16A3 (0.55) SMN1; SMN2F2RSLC16A3RXFP1LMNA
N-Phenylbenzamide SCHEMBL4874327 0.86 KCNK3 (0.57) F2RSLC16A3RXFP1KCNK3KCNK9
SCHEMBL4671630 0.85 SMN1; SMN2 (0.54) SMN1; SMN2F2RSLC16A3RXFP1LMNA
SCHEMBL4874318 0.84 SLC16A3 (0.47) SMN1; SMN2F2RSLC16A3GRM5PLK1
SCHEMBL10943427 0.84 SMN1; SMN2 (0.53) SMN1; SMN2F2RSLC16A3RXFP1LMNA
SCHEMBL12893297 0.84 SMN1; SMN2 (0.53) SMN1; SMN2F2RSLC16A3RXFP1LMNA
SCHEMBL13645650 0.84 SMN1; SMN2 (0.56) SMN1; SMN2F2RRXFP1LMNAGAA
SCHEMBL10942213 0.82 SMN1; SMN2 (0.52) SMN1; SMN2F2RSLC16A3RXFP1LMNA
SCHEMBL12742754 0.81 SMN1; SMN2 (0.51) SMN1; SMN2F2RSLC16A3RXFP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7314958-B2 Phenylbenzamides BAYER CROPSCIENCE AG (DE) 2008-01-01 US disclosed
US-7314958-B2 Phenylbenzamides BAYER CROPSCIENCE AG (DE) 2008-01-01 US disclosed