Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10238203 | 0.87 | ATM (0.47) | ATMMAPTLMNAGAAMAPK1 | |
| SCHEMBL10238267 | 0.85 | ATM (0.46) | ATMMAPTLMNAGAAMAPK1 | |
| SCHEMBL13645577 | 0.82 | MEN1 (0.47) | MAPTLMNAGAAMAPK1TDP1 | |
| SCHEMBL13292661 | 0.79 | MAPK1 (0.47) | MAPTLMNAGAAMAPK1PKM | |
| SCHEMBL2906958 | 0.78 | CYP1A2 (0.56) | TDP1POLBALDH1A1 | |
| SCHEMBL13645670 | 0.78 | SMN1; SMN2 (0.48) | ATMLMNAGAATDP1ALDH1A1 | |
| SCHEMBL13292781 | 0.78 | MAPT (0.39) | MAPTLMNAGAAMAPK1TDP1 | |
| SCHEMBL646049 | 0.76 | ATM (0.53) | ATMGAAPOLBALDH1A1NAMPT | |
| SCHEMBL16133857 | 0.76 | ATM (0.53) | ATMLMNAGAAPOLBNAMPT | |
| SCHEMBL645503 | 0.76 | ATM (0.76) | ATMMAPTLMNAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598389-B2 | Silylated carboxamides | BAYER CROPSCIENCE AG (DE) | 2009-10-06 | — | — | US | disclosed |
| US-20070191454-A1 | Silylated carboxamides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191454-A1 | Silylated carboxamides | MRPL21, MRPS22, MRPS34 | ATM 4099/4885MAPT 3363/4885LMNA 2134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.