⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6636855 | 0.67 | — | — | |
| SCHEMBL9966682 | 0.62 | — | — | |
| SCHEMBL1550826 | 0.62 | — | — | |
| SCHEMBL27485944 | 0.62 | — | — | |
| SCHEMBL2218606 | 0.61 | — | — | |
| Bromide SCHEMBL28296934 | 0.61 | — | — | |
| SCHEMBL13188014 | 0.60 | — | — | |
| SCHEMBL787457 | 0.60 | — | — | |
| SCHEMBL8214878 | 0.57 | — | — | |
| SCHEMBL12550550 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116802176-A | Oxindoles and methods of use thereof | 阿利戈斯治疗公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-116655522-A | Derivative of polycyclic nitroxide free radical structural unit, preparation method and application thereof | 西安交通大学 | 2023-08-29 | — | — | CN | disclosed |
| US-9440958-B2 | Substituted cyclic hydroxamates as inhibitors of matrix metalloproteinases | INCYTE CORPORATION (US) | 2016-09-13 | — | — | US | disclosed |
| US-20150025056-A1 | SUBSTITUTED CYCLIC HYDROXAMATES AS INHIBITORS OF MATRIX METALLOPROTEINASES | INCYTE CORPORATION (US) | 2015-01-22 | — | — | US | disclosed |
| US-8853243-B2 | Substituted cyclic hydroxamates as inhibitors of matrix metalloproteinases | INCYTE CORPORATION (US) | 2014-10-07 | — | — | US | disclosed |
| US-8569521-B2 | Benzenesulfonyl-chromane, thiochromane, tetrahydronaphthalene and related gamma secretase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2013-10-29 | — | — | US | disclosed |
| EP-1976843-B1 | CARBOCYCLIC AND HETEROCYCLIC ARYLSULFONES AS GAMMA SECRETASE INHIBITORS | MERCK SHARP & DOHME (US) | 2013-09-04 | — | — | EP | disclosed |
| US-20120264736-A1 | BENZENESULFONYL-CHROMANE, THIOCHROMANE, TETRAHYDRONAPHTHALENE AND RELATED GAMMA SECRETASE INHIBITORS | SCHERING CORPORATION (US) | 2012-10-18 | — | — | US | disclosed |
| US-8067621-B2 | Benzenesulfonyl-chromane, thiochromane, tetrahydronaphthalene and related gamma secretase inhibitors | SCHERING CORPORATION (US) | 2011-11-29 | — | — | US | disclosed |
| US-20110224189-A1 | SUBSTITUTED CYCLIC HYDROXAMATES AS INHIBITORS OF MATRIX METALLOPROTEINASES | INCYTE CORPORATION | 2011-09-15 | — | — | US | disclosed |
| US-6211265-B1 | INKS WITH BLACK, YELLOW, CYAN AND MAGENTA COLORS WITH CATIONIC POLYMERS | SEIKO EPSON CORPORATION (JP) | 2001-04-03 | — | — | US | disclosed |
| US-6156940-A | Process for producing optically active carbinols | SUMIKA FINE CHEMICALS COMPANY, LIMITED (JP) | 2000-12-05 | — | — | US | disclosed |
| US-6100315-A | A NONCLOGGING, WATER SOLUBLE COLOR MIXTURE CONTAINING A CATIONIC, WATER-SOLUBLE POLYMER, WATER-SOLUBLE ANTIDEPOSIT AGENT TO YIELD AN IMAGE HAVING GOOD WATERFASTNESS | SEIKO EPSON CORPORATION (JP) | 2000-08-08 | — | — | US | disclosed |
| EP-0713848-B1 | Process for producing optically active carbinols | SUMIKA FINE CHEMICALS COMPANY (JP) | 1999-09-08 | — | — | EP | disclosed |
| EP-0911374-A1 | WATER BASE INK SET FOR INK JET RECORDING | SEIKO EPSON CORPORATION (JP) | 1999-04-28 | — | — | EP | disclosed |
| EP-0909798-A1 | INKS FOR INK-JET RECORDING | SEIKO EPSON CORPORATION (JP) | 1999-04-21 | — | — | EP | disclosed |
| US-5831132-A | REDUCING AGENT FROM BORANES AND AMINO ALCOHOLS | SUMIKA FINE CHEMICALS COMPANY, LTD. (JP) | 1998-11-03 | — | — | US | disclosed |
| WO-1997049708-A9 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | — | 1998-05-22 | — | — | WO | disclosed |
| EP-0713848-A1 | Process for producing optically active carbinols | SUMIKA FINE CHEMICALS Company, Limited (JP) | 1996-05-29 | — | — | EP | disclosed |
| EP-0397456-A1 | Polyester resin composition and molded articles thereof | POLYPLASTICS CO. LTD. (JP) | 1990-11-14 | — | — | EP | disclosed |