Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 16/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3865747 | 0.84 | NLRP3 (0.54) | NLRP3TLR7TLR8 | |
| SCHEMBL483316 | 0.81 | NLRP3 (0.50) | NLRP3TLR7TLR8 | |
| SCHEMBL30345870 | 0.81 | NLRP3 (0.50) | NLRP3TLR7TLR8 | |
| SCHEMBL3865444 | 0.81 | TLR7 (0.48) | NLRP3TLR7TLR8 | |
| SCHEMBL3862522 | 0.76 | TLR7 (0.43) | NLRP3TLR7 | |
| SCHEMBL3865082 | 0.76 | NLRP3 (0.54) | NLRP3TLR7TLR8 | |
| SCHEMBL483361 | 0.76 | KDM4E (0.45) | NLRP3TLR7 | |
| SCHEMBL30345871 | 0.76 | KDM4E (0.45) | NLRP3TLR7 | |
| SCHEMBL4534287 | 0.75 | TLR7 (0.45) | NLRP3TLR7 | |
| SCHEMBL1754006 | 0.74 | NLRP3 (0.55) | NLRP3TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598382-B2 | Aryl substituted imidazoquinolines | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2009-10-06 | — | — | US | disclosed |
| US-7598382-B2 | Aryl substituted imidazoquinolines | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2009-10-06 | — | — | US | disclosed |