Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | NAMPT | P43490 | 6/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TACR2 | P21452 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13646279 | 0.97 | NAMPT (0.48) | POLBNAMPTHDAC1HDAC6MEN1 | |
| SCHEMBL3836221 | 0.89 | POLB (0.48) | POLBNAMPTHDAC1HDAC6MEN1 | |
| SCHEMBL2476313 | 0.87 | POLB (0.52) | POLBNAMPTHDAC1HDAC6MEN1 | |
| SCHEMBL13646265 | 0.86 | NAMPT (0.47) | POLBNAMPTHDAC1ALDH1A1TSHR | |
| SCHEMBL13646268 | 0.86 | HSD17B10 (0.43) | POLBNAMPTHDAC1HDAC6KMT2A | |
| SCHEMBL13646307 | 0.86 | HSD17B10 (0.48) | POLBNAMPTHDAC1HDAC6KDM4E | |
| SCHEMBL3835937 | 0.86 | NAMPT (0.48) | POLBNAMPTHDAC1HDAC6MEN1 | |
| SCHEMBL13646306 | 0.84 | HSD17B10 (0.47) | POLBNAMPTMEN1KMT2AKDM4E | |
| SCHEMBL12051883 | 0.83 | NAMPT (0.51) | POLBNAMPTHDAC1HDAC6MEN1 | |
| SCHEMBL13646250 | 0.82 | ALDH1A1 (0.51) | POLBNAMPTKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2107052-A1 | NOVEL N-(2-AMINOPHENYL)BENZAMIDE DERIVATIVE HAVING AN UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2009-10-07 | — | — | EP | disclosed |