Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.35 |
| ▸ | CHRNA10 | Q9GZZ6 | 3/20 | 0.35 |
| ▸ | CHRNA9 | Q9UGM1 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3836316 | 0.87 | HTT (0.39) | HTTCTDSP1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL3835692 | 0.86 | HTT (0.41) | HTTCTDSP1CHRNB2CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL3856358 | 0.85 | HTT (0.38) | HTTCTDSP1CHRNB2CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL3851712 | 0.84 | HTT (0.39) | HTTCTDSP1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL3835781 | 0.78 | CTDSP1 (0.38) | HTTCTDSP1CHRNB2CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL3854777 | 0.77 | CTDSP1 (0.37) | HTTCTDSP1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL21388271 | 0.72 | HTT (0.49) | HTTCTDSP1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL18937045 | 0.68 | HTT (0.37) | HTTCTDSP1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL3839662 | 0.68 | CHRNB2 (0.34) | HTTCTDSP1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL3835752 | 0.67 | CHRNB2 (0.35) | HTTCTDSP1CHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1792903-B1 | Composition for the dyeing of keratin fibres comprising at least one cationic 3-amino-pyrazolopyridine derivative | OREAL (FR) | 2009-10-14 | — | — | EP | disclosed |