Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | USP2 | O75604 | 3/20 | 0.33 |
| ▸ | CRHBP | P24387 | 2/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.33 |
| ▸ | IDE | P14735 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6522037 | 0.84 | PPARG (0.36) | PPARGMAPTMEN1KMT2AUSP2 | |
| SCHEMBL6522033 | 0.84 | PPARG (0.36) | PPARGMAPTMEN1KMT2AUSP2 | |
| SCHEMBL6522028 | 0.84 | PPARG (0.36) | PPARGMAPTMEN1KMT2AUSP2 | |
| SCHEMBL11460156 | 0.81 | BCHE (0.34) | PPARGMAPTMEN1KMT2AUSP2 | |
| SCHEMBL28863165 | 0.76 | ALDH1A1 (0.35) | PPARGMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL6426503 | 0.74 | MAPT (0.54) | MAPTMEN1KMT2AUSP2CRHBP | |
| SCHEMBL21126650 | 0.73 | MAPT (0.34) | PPARGMAPTMEN1KMT2AUSP2 | |
| Iodide SCHEMBL31607475 | 0.73 | MAPT (0.53) | MAPTMEN1KMT2AUSP2CRHBP | |
| SCHEMBL514686 | 0.71 | ALDH1A1 (0.35) | PPARGMAPTALDH1A1HPGDHTT | |
| SCHEMBL20717990 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1627635-B1 | Benzothiazolium compounds for use in methods of inhibiting NO production and TNF alpha and treating coronaviral infection | NAT HEALTH RESEARCH INSTITUTES (TW) | 2009-10-07 | — | — | EP | disclosed |