Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13999137 | 0.87 | KDM4E (0.49) | KDM4ECYP1A2HDAC1HDAC6ERN1 | |
| SCHEMBL13647144 | 0.71 | IDO1 (0.41) | ALOX15 | |
| SCHEMBL7928877 | 0.69 | CYP1A2 (0.42) | KDM4ECYP1A2HDAC1HDAC6 | |
| SCHEMBL28450996 | 0.67 | CYP1A2 (0.40) | KDM4ECYP1A2PDE4A | |
| SCHEMBL28435022 | 0.67 | KDM4E (0.46) | KDM4ECYP1A2PDE4APDE4BPDE4C | |
| SCHEMBL19050329 | 0.66 | CYP1A2 (0.36) | KDM4ECYP1A2 | |
| SCHEMBL19050081 | 0.66 | CYP1A2 (0.36) | KDM4ECYP1A2 | |
| SCHEMBL29822725 | 0.65 | ALOX15 (0.32) | ALOX15 | |
| SCHEMBL20152958 | 0.64 | HPGD (0.39) | KDM4EALOX15MAPT | |
| SCHEMBL30785796 | 0.64 | HPGD (0.39) | KDM4EALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7470376-B2 | Photochemically active chiral compounds and compositions containing the same | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2008-12-30 | — | — | US | disclosed |