⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27599259 | 0.79 | — | — | |
| SCHEMBL10792704 | 0.79 | — | — | |
| SCHEMBL3119781 | 0.78 | GABRR1 (0.45) | — | |
| SCHEMBL18652450 | 0.78 | TRPA1 (0.43) | — | |
| SCHEMBL3117322 | 0.75 | BLM (0.46) | — | |
| SCHEMBL1457046 | 0.74 | TRPA1 (0.43) | — | |
| SCHEMBL18650209 | 0.74 | TRPA1 (0.39) | — | |
| SCHEMBL541691 | 0.72 | GABRR1 (0.46) | — | |
| SCHEMBL15895653 | 0.72 | — | — | |
| SCHEMBL9011931 | 0.71 | TRPA1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104024306-B | The conjugate and its medical application of polyoxazoline polymer and preparation method thereof, these polymer | 根特大学 | 2017-06-13 | — | — | CN | disclosed |
| US-9180202-B2 | Polyoxazoline polymers and methods for their preparation, conjugates of these polymers and medical uses thereof | UNIVERSITEIT GENT (BE) | 2015-11-10 | — | — | US | disclosed |
| US-20150025196-A1 | POLYOXAZOLINE POLYMERS AND METHODS FOR THEIR PREPARATION, CONJUGATES OF THESE POLYMERS AND MEDICAL USES THEREOF | UNIVERSITEIT GENT (BE) | 2015-01-22 | — | — | US | disclosed |
| EP-2800773-A1 | POLYOXAZOLINE POLYMERS AND METHODS FOR THEIR PREPARATION, CONJUGATES OF THESE POLYMERS AND MEDICAL USES THEREOF | Universiteit Gent (BE) | 2014-11-12 | — | — | EP | disclosed |
| CN-104024306-A | POLYOXAZOLINE POLYMERS AND METHODS FOR THEIR PREPARATION, CONJUGATES OF THESE POLYMERS AND MEDICAL USES THEREOF | UNIV GENT | 2014-09-03 | — | — | CN | disclosed |
| WO-2013103297-A1 | POLYOXAZOLINE POLYMERS AND METHODS FOR THEIR PREPARATION, CONJUGATES OF THESE POLYMERS AND MEDICAL USES THEREOF | UNIVERSITEIT GENT (BE) | 2013-07-11 | — | — | WO | disclosed |
| US-8445214-B2 | Preparation of micro-porous crystals and conjugates thereof | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2013-05-21 | — | — | US | disclosed |
| US-20110287408-A1 | Preparation of Micro-Porous Crystals and Conjugates Thereof | UNIVERSITAET BERN (CH) | 2011-11-24 | — | — | US | disclosed |
| US-7960124-B2 | Zeolite labeled with dye, stop-cock moiety, and affinity binding agent; visualized using magnetic resonance imaging and computed tomography | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2011-06-14 | — | — | US | disclosed |
| EP-2089320-B1 | METHOD FOR THE PREPARATION OF MICRO-POROUS CRYSTALS AND CONJUGATES THEREOF | ROCHE DIAGNOSTICS GMBH (DE) | 2010-10-20 | — | — | EP | disclosed |
| EP-2089320-A1 | METHOD FOR THE PREPARATION OF MICRO-POROUS CRYSTALS AND CONJUGATES THEREOF | Roche Diagnostics GmbH (DE) | 2009-08-19 | — | — | EP | disclosed |
| US-20080138914-A1 | Preparation of micro-porous crystals and conjugates thereof | WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER (DE) | 2008-06-12 | — | — | US | disclosed |
| WO-2008052603-A1 | METHOD FOR THE PREPARATION OF MICRO-POROUS CRYSTALS AND CONJUGATES THEREOF | ROCHE DIAGNOSTICS GMBH (DE) | 2008-05-08 | — | — | WO | disclosed |