Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2484323 | 0.71 | TSHR (0.44) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL12694792 | 0.71 | TSHR (0.44) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL2484324 | 0.71 | TSHR (0.44) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| Triacetin SCHEMBL3412490 | 0.68 | TDP1 (0.47) | TDP1TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL1079198 | 0.68 | TDP1 (0.56) | TDP1TSHRALDH1A1LMNAHSD17B10 | |
| Triacetin SCHEMBL821340 | 0.68 | TDP1 (0.56) | TDP1TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL12846719 | 0.68 | TDP1 (0.75) | TDP1TSHRALDH1A1LMNAHSD17B10 | |
| Triacetin SCHEMBL3870 | 0.68 | TDP1 (0.56) | TDP1TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL7150206 | 0.68 | TDP1 (0.75) | TDP1TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL8723281 | 0.68 | TDP1 (0.75) | TDP1TSHRALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1356033-B1 | METHYL-D-ERYTHRITOL PHOSPHATE PATHWAY GENES | MONSANTO TECHNOLOGY LLC (US) | 2009-10-28 | — | — | EP | disclosed |
| US-20080244790-A1 | METHYL-D-ERYTHRITOL PHOSPHATE PATHWAY GENES | BORONAT ALBERT | 2008-10-02 | — | — | US | disclosed |
| US-7405343-B2 | Methyl-D-erythritol phosphate pathway genes | MONSANTO TECHNOLOGY LLC (US) | 2008-07-29 | — | — | US | disclosed |