Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.75 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PGD | P52209 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7150206 | 1.00 | TDP1 (0.75) | TDP1TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL12846719 | 1.00 | TDP1 (0.75) | TDP1TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL9426447 | 0.93 | TDP1 (0.67) | TDP1TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL8447422 | 0.93 | TDP1 (0.67) | TDP1TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL7218077 | 0.91 | TDP1 (0.64) | TDP1TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL7757654 | 0.91 | TDP1 (0.64) | TDP1TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL16546894 | 0.91 | TDP1 (0.64) | TDP1TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL11846043 | 0.89 | TDP1 (0.62) | TDP1TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL17277235 | 0.88 | TDP1 (0.67) | TDP1TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL2175855 | 0.88 | TDP1 (0.96) | TDP1TSHRALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3634430-B1 | MULTIBIOTIC AGENTS AND METHODS OF USING THE SAME | FLAGSHIP PIONEERING INNOVATIONS V INC (US) | 2024-08-07 | — | — | EP | disclosed |
| US-20230293458-A1 | MULTIBIOTIC AGENTS AND METHODS OF USING THE SAME | FLAGSHIP PIONEERING INNOVATIONS V INC (US) | 2023-09-21 | — | — | US | disclosed |
| CN-115873288-B | Temperature-sensitive PCR thin-wall tube | 杭州皓丰生物技术有限公司 | 2023-05-12 | — | — | CN | disclosed |
| CN-115873288-A | Temperature-sensitive PCR (polymerase chain reaction) thin-walled tube | 杭州皓丰生物技术有限公司 | 2023-03-31 | — | — | CN | disclosed |
| US-11253538-B2 | Methods and materials for reducing amyloid beta levels within a mammal | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2022-02-22 | — | — | US | disclosed |
| US-11160825-B2 | Methods and materials for treating diabetes or liver steatosis | RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK (US) | 2021-11-02 | — | — | US | disclosed |
| US-20200268787-A1 | METHODS AND MATERIALS FOR REDUCING AMYLOID BETA LEVELS WITHIN A MAMMAL | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK | 2020-08-27 | — | — | US | disclosed |
| US-10639322-B2 | Methods and materials for reducing amyloid beta levels within a mammal | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2020-05-05 | — | — | US | disclosed |
| EP-3634430-A1 | MULTIBIOTIC AGENTS AND METHODS OF USING THE SAME | Flagship Pioneering Innovations V, Inc. (US) | 2020-04-15 | — | — | EP | disclosed |
| US-20200101030-A1 | MULTIBIOTIC AGENTS AND METHODS OF USING THE SAME | KINTAI THERAPEUTICS, INC. | 2020-04-02 | — | — | US | disclosed |
| WO-2018226732-A1 | MULTIBIOTIC AGENTS AND METHODS OF USING THE SAME | FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) | 2018-12-13 | — | — | WO | disclosed |
| US-20180078575-A1 | METHODS AND MATERIALS FOR REDUCING AMYLOID BETA LEVELS WITHIN A MAMMAL | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK | 2018-03-22 | — | — | US | disclosed |
| US-20180078599-A1 | METHODS AND MATERIALS FOR TREATING CANCER | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK | 2018-03-22 | — | — | US | disclosed |
| US-20170232033-A1 | METHODS AND MATERIALS RELATED TO NUTRITIONAL SUPPLEMENT COMPOSITIONS CONTAINING A POTATO POLYSACCHARIDE PREPARATION | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2017-08-17 | — | — | US | disclosed |
| US-20160362535-A1 | 5H-FURAN-2-ONE DERIVATIVES STABILIZATION OF ORGANIC MATERIAL | BASF SCHWEIZ AG (CH) | 2016-12-15 | — | — | US | disclosed |
| WO-2016160590-A1 | METHODS AND MATERIALS FOR TREATING CANCER | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2016-10-06 | — | — | WO | disclosed |
| WO-2016160594-A1 | METHODS AND MATERIALS FOR REDUCING AMYLOID BETA LEVELS WITHIN A MAMMAL | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2016-10-06 | — | — | WO | disclosed |
| WO-2015041837-A1 | METHODS AND MATERIALS FOR TREATING DIABETES OR LIVER STEATOSIS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2015-03-26 | — | — | WO | disclosed |
| WO-2012150527-A1 | 5H-FURAN-2-ONE DERIVATIVES FOR STABILIZATION OF ORGANIC MATERIAL | BASF SE (DE) | 2012-11-08 | — | — | WO | disclosed |
| EP-0832898-A2 | Substituted amino acid derivatives | BAYER AG (DE) | 1998-04-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200268787-A1 | METHODS AND MATERIALS FOR REDUCING AMYLOID BETA LEVELS WITHIN A MAMMAL | PYGB, APP, IAPP | TDP1 1026/4885TSHR 4295/4885ALDH1A1 4469/4885 |
| US-20180078575-A1 | METHODS AND MATERIALS FOR REDUCING AMYLOID BETA LEVELS WITHIN A MAMMAL | PYGB, APP, IAPP | TDP1 1026/4885TSHR 4295/4885ALDH1A1 4469/4885 |
| US-11253538-B2 | Methods and materials for reducing amyloid beta levels within a mammal | PYGB, APP, IAPP | TDP1 1026/4885TSHR 4295/4885ALDH1A1 4469/4885 |
| US-20180078599-A1 | METHODS AND MATERIALS FOR TREATING CANCER | KRAS, TP53, HRAS | TDP1 2947/4885TSHR 3713/4885ALDH1A1 4520/4885 |
| US-20200101030-A1 | MULTIBIOTIC AGENTS AND METHODS OF USING THE SAME | SI, FABP2, CEL | TDP1 2978/4885TSHR 4527/4885ALDH1A1 1112/4885 |
| US-20230293458-A1 | MULTIBIOTIC AGENTS AND METHODS OF USING THE SAME | SI, FABP2, CEL | TDP1 2978/4885TSHR 4527/4885ALDH1A1 1112/4885 |
| US-11160825-B2 | Methods and materials for treating diabetes or liver steatosis | GYS2, PYGL, LIPC | TDP1 3662/4885TSHR 3200/4885ALDH1A1 3759/4885 |
| US-10639322-B2 | Methods and materials for reducing amyloid beta levels within a mammal | PYGB, APP, IAPP | TDP1 1026/4885TSHR 4295/4885ALDH1A1 4469/4885 |
| US-20170232033-A1 | METHODS AND MATERIALS RELATED TO NUTRITIONAL SUPPLEMENT COMPOSITIONS CONTAINING A POTATO POLYSACCHARIDE PREPARATION | CS, PC, GYS1 | TDP1 2309/4885TSHR 4351/4885ALDH1A1 4753/4885 |
| US-20160362535-A1 | 5H-FURAN-2-ONE DERIVATIVES STABILIZATION OF ORGANIC MATERIAL | C5, C9, CBR1 | TDP1 2815/4885TSHR 3646/4885ALDH1A1 188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.