Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22171121 | 0.88 | PAOX (0.57) | USP2TSHRPAOXKMT2ACYP2C19 | |
| SCHEMBL100593 | 0.86 | — | — | |
| SCHEMBL26170580 | 0.86 | ALDH1A1 (0.50) | TSHRPAOXMMP8DPP7EPHX1 | |
| SCHEMBL13933505 | 0.84 | TSHR (0.48) | USP2TSHRKMT2ACYP2C19CYP2D6 | |
| Hydrochloric Acid SCHEMBL29172352 | 0.84 | USP2 (0.46) | USP2TSHRKMT2ACYP2C19CYP2D6 | |
| SCHEMBL22203823 | 0.83 | PAOX (0.45) | USP2TSHRPAOXKMT2ACYP2C19 | |
| SCHEMBL12131751 | 0.83 | USP2 (0.55) | USP2TSHRKMT2ACYP2C19CYP2D6 | |
| SCHEMBL22171087 | 0.83 | KMT2A (0.46) | USP2TSHRKMT2ACYP2C19CYP2D6 | |
| SCHEMBL16384387 | 0.83 | TSHR (0.41) | USP2TSHRKMT2ACYP2C19CYP2D6 | |
| SCHEMBL12522545 | 0.83 | PAOX (0.45) | USP2TSHRPAOXKMT2ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021195465-A1 | TREATMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME AND RELATED CONDITIONS WITH ANTAGONISTS OF E-SELECTIN | MAGNANI JOHN L (US) | 2021-09-30 | — | — | WO | disclosed |
| US-7597884-B2 | Hyperglycosylated polypeptide variants and methods of use | ALIOS BIOPHARMA, INC. (US) | 2009-10-06 | — | — | US | disclosed |