Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 15/20 | 0.53 |
| ▸ | CSNK2A2 | P19784 | 15/20 | 0.53 |
| ▸ | CSNK2B | P67870 | 15/20 | 0.53 |
| ▸ | PIM3 | Q86V86 | 15/20 | 0.53 |
| ▸ | PIM2 | Q9P1W9 | 15/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1848526 | 0.81 | PIM1 (0.74) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL1851322 | 0.80 | CSNK2B (0.70) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL13657347 | 0.78 | PIM1 (0.74) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL23692913 | 0.72 | CYP1A2 (0.49) | CYP1A1CYP1A2CYP1B1TP53 | |
| SCHEMBL11821683 | 0.72 | TNKS (0.71) | CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL17829780 | 0.71 | TNKS (0.57) | PIM1IDO1MGAMGAASI | |
| SCHEMBL23692915 | 0.71 | CYP1A2 (0.47) | CYP1A1CYP1A2CYP1B1TP53 | |
| SCHEMBL17829660 | 0.69 | TNKS (0.72) | MGAMGAASIMGAM2 | |
| SCHEMBL20696307 | 0.69 | CYP1A1 (0.41) | PIM1CYP1A1CYP1A2CYP1B1IDO1 | |
| SCHEMBL20679985 | 0.69 | CYP1A1 (0.41) | PIM1CYP1A1CYP1A2CYP1B1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247559-A1 | Benzofuropyrimidinones | EXELIXIS, INC. (US) | 2009-10-01 | — | — | US | disclosed |
| US-20090247559-A1 | Benzofuropyrimidinones | EXELIXIS, INC. (US) | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247559-A1 | Benzofuropyrimidinones | F12, BRI3BP, BRD1 | PIM1 1977/4885CSNK2A2 906/4885CSNK2B 350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.