Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 20/20 | 0.74 |
| ▸ | CSNK2B | P67870 | 19/20 | 0.74 |
| ▸ | PIM3 | Q86V86 | 18/20 | 0.74 |
| ▸ | PIM2 | Q9P1W9 | 18/20 | 0.74 |
| ▸ | CSNK2A2 | P19784 | 18/20 | 0.74 |
| ▸ | CDC7 | O00311 | 3/20 | 0.54 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.54 |
| ▸ | GSK3B | P49841 | 2/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.54 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.54 |
| ▸ | IGF1R | P08069 | 1/20 | 0.54 |
| ▸ | CLK2 | P49760 | 1/20 | 0.54 |
| ▸ | GSK3A | P49840 | 1/20 | 0.54 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.54 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.54 |
| ▸ | CIT | O14578 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.54 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1851446 | 0.85 | PIM1 (1.00) | PIM1CSNK2BPIM3PIM2CSNK2A2 | |
| SCHEMBL1856370 | 0.83 | CSNK2B (0.74) | PIM1CSNK2BPIM3PIM2CSNK2A2 | |
| SCHEMBL1851322 | 0.82 | CSNK2B (0.70) | PIM1CSNK2BPIM3PIM2CSNK2A2 | |
| SCHEMBL13650745 | 0.82 | CSNK2B (0.73) | PIM1CSNK2BPIM3PIM2CSNK2A2 | |
| SCHEMBL1849963 | 0.80 | PIM1 (1.00) | PIM1CSNK2BPIM3PIM2CSNK2A2 | |
| SCHEMBL4573688 | 0.79 | PIM1 (0.62) | PIM1CSNK2BPIM3PIM2CSNK2A2 | |
| SCHEMBL13650796 | 0.78 | PIM1 (0.53) | PIM1CSNK2BPIM3PIM2CSNK2A2 | |
| SCHEMBL913665 | 0.77 | CASP3 (0.52) | PIM1CSNK2BPIM3PIM2CSNK2A2 | |
| SCHEMBL1852869 | 0.77 | PIM1 (0.67) | PIM1CSNK2BPIM3PIM2CSNK2A2 | |
| SCHEMBL1853268 | 0.77 | CSNK2B (0.67) | PIM1CSNK2BPIM3PIM2CSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247559-A1 | Benzofuropyrimidinones | EXELIXIS, INC. (US) | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247559-A1 | Benzofuropyrimidinones | F12, BRI3BP, BRD1 | PIM1 1977/4885CSNK2B 350/4885PIM3 1498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.