Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.54 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.54 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | BACE1 | P56817 | 2/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4228676 | 0.99 | GRM2 (0.53) | GRM2GRM3BCHEACHEBACE1 | |
| Hydrochloric Acid SCHEMBL4228675 | 0.99 | GRM2 (0.53) | GRM2GRM3BCHEACHEBACE1 | |
| Hydrochloric Acid SCHEMBL4215940 | 0.92 | GRM2 (0.52) | GRM2GRM3BCHEACHEBACE1 | |
| Hydrochloric Acid SCHEMBL4215931 | 0.92 | GRM2 (0.52) | GRM2GRM3BCHEACHEBACE1 | |
| SCHEMBL4214481 | 0.91 | GRM2 (0.57) | GRM2GRM3BCHEACHEBACE1 | |
| SCHEMBL4214482 | 0.91 | GRM2 (0.57) | GRM2GRM3BCHEACHEBACE1 | |
| SCHEMBL13651271 | 0.87 | GRM2 (0.53) | GRM2GRM3BCHEACHEBACE1 | |
| Hydrochloric Acid SCHEMBL4219962 | 0.86 | GRM2 (0.52) | GRM2GRM3BCHEACHEBACE1 | |
| Hydrochloric Acid SCHEMBL4219956 | 0.86 | GRM2 (0.52) | GRM2GRM3BCHEACHEBACE1 | |
| SCHEMBL13651262 | 0.85 | GRM2 (0.58) | GRM2GRM3BCHEACHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009131196-A1 | SUBSTITUTED PYRROLIDINE DERIVATIVE AND USE THEREOF | 武田薬品工業株式会社 (JP) | 2009-10-29 | — | — | WO | disclosed |